Homocysteine Level and Cardiovascular Disease Risk Factors: A Population Based Cross- Sectional Study

Journal of the Anthropological Survey of India, 66(1-2) : (19-33), 2017

Homocysteine Level and Cardiovascular Disease Risk Factors: A Population Based Cross- Sectional Study

Astha Bansal and P. C. Joshi
Department of Anthropology, University of Delhi, Delhi

Abstract
Cardiovascular disease (CVD) is a leading cause of death around the globe. Elevated concentration of homocysteine levels may also increase the incidence of CVDs. There is association between increased levels of homocysteine and cardiovascular risk variables. An understanding of the interaction between homocysteine and cardiovascular risk variables may offer novel ways of managing cardiovascular disease. The present study attempts to find an association between homocysteine and cardiovascular risk factors among Sunni Muslims of Delhi, India. A cross sectional study of Sunni Muslims was conducted using a household survey in Urban Delhi. A total of 406 Sunni Muslims (125 males and 281 females) between 35 and 65 years of age were included using random sampling method. Finding show that male sex, increased age, increased serum creatinine level, increased triglycerides, deficiencies of folate and vitamin B12 and fasting blood glucose are the important determinants of homocysteine concentration with interaction effects between these factors in a community-based Sunni Muslim population of Delhi. Further research is needed for better understanding of the combined effect of the pathways in order to prevent cardiovascular problem in a novel way.

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